Dr. de Bold was born in Argentina, and later studied at the National University of Cordoba there. He is now married and has five children. In 1968, Dr. de Bold came to Canada as a graduate student in the department of Pathology at Queen's University in Kingston, Ontario, Canada, where he received his MSc and PhD degrees in Pathology. In 1973, he was appointed Assistant Professor of Pathology at Queen's University where his career as an independent investigator began. Although Dr. de Bold trained primarily in biochemistry, he also studied as an experimental pathologist during his graduate work. He used his combined skills to study the cell biology of the mammalian atrial cardiocyte (heart muscle cell). He also investigated the cell biology of the pancreatic beta cells and cells of the pars intermedia of the pituitary gland. His researches on the heart led him to the 1980 discovery of Atrial Natriuretic Factor (ANF): a polypeptide hormone produced by the cardiac muscle cell of the heart atrium. He thus demonstrated that the heart has an endocrine function and opened a field of research that has led to many new insights in biology. At present Dr. de Bold is Professor of Pathology and Physiology at the University of Ottawa, Distinguished Research Professor of the Ontario Heart and Stroke Foundation and Director of the Cardiac Cell and Molecular Biology Laboratory at the University of Ottawa Heart Institute.
Recognition of his work on ANF is shown by his numerous distinctions and awards, including the Gairdner Foundation International Award, The Royal Society of Canada McLaughlin Medal in Medical Research, The Ernest C. Manning Principal Award, The International Society for Hypertension Research Award, the American Society for Hypertension Award and the CIBA Award in Hypertension Research, Council for High Blood Pressure Research, American Heart Association among others. He is a Nobel Prize nominee, a fellow of the Royal Society of Canada and of the Royal College of Physicians and Surgeons and an Officer of the Order of Canada. He has been a board member of several institutions including the National Research Council of Canada, the Ontario Heart and Stroke Foundation of Canada and the University of Ottawa Heart Institute at the Ottawa Civic Hospital.
Source: de Bold
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